In this study we performed a calculation of the tectonic stress tensor based on fault slip data and all available focal mechanisms in order to determine the principal stress axes and the recent tectonic regime of the westernmost unit of the Getic nappe system (Gornjak-Ravanica Zone, Eastern Serbia). The study is based on a combined dataset involving paleostress analyses, the inversion of focal mechanisms and remote sensing. The results show dominant strike-slip kinematics with the maximal compression axis oriented NNE—SSW. This is compatible with a combined northward motion and counterclockwise rotation of the Adria plate as the controlling factor. However, the local stress field is also shown to be of great importance and is superimposed on the far-field stress. We managed to distinguish three areas with distinct seismic activity. The northern part of the research area is characterized by transtensional tectonics, possibly under the influence of the extension in the areas situated more to the northeast. The central and seismically most active part is dominated by strike-slip tectonics whereas the southern area is slightly transpressional, possibly under the influence of the rigid Moesian Platform situated to the east of the research area. The dominant active fault systems are oriented N—S (to NE—SW) and NW—SE and they occur as structures of either regional or local significance. Regional structures are active in the northern and central part of the study area, while the active fault systems in the southern part are marked as locally important. This study suggests that seismicity of this area is controlled by the release of accumulated stress at local accommodation zones which are favourably oriented in respect to the active regional stress field.