The Abu Kharif peralkaline granite (AKPG) with Ediacaran age in the Eastern Desert of Egypt, as a part of the Arabian–Nubian Shield (ANS), hosts abundant finer-grained microgranular enclaves (MEs). Such MEs are rare in peralkaline A-type granites, and their origin remains poorly constrained. The Abu Kharif MEs and host granite share similar mineral assemblages, including albite (Ab₉₉An₁), K-feldspar (Or₉₇Ab₃), ferroan Na–Ca amphibole (mostly ferro-richterite, katophorite, and ferro-winchite), Mn-rich ilmenite (up to 12.8 wt.% of MnO), quartz, and Ti-rich magnetite (up to 15.6 wt.% of TiO₂), but differ in modal proportions. Titanite occurs exclusively in the enclaves and is interpreted to be hydrothermal in origin, where it replaces amphibole. Furthermore, Mn-rich ilmenite, Ti-rich magnetite, and zircon are more abundant in the host granite, while quartz is less abundant in the enclaves. Overall, the MEs are rich in mafic minerals – particularly amphibole, titanite, and ilmenite – comprising >50 vol.% of the mode, which is inconsistent with a liquid composition. Their field, mineralogical, and textural characteristics instead support a cogenetic origin, consistent with autolithic model. The finer grain size of the MEs reflects crystallization under undercooling conditions, likely at magma chamber margins during the emplacement, while their ellipsoidal shapes and mineralogical similarity to the host granite indicate plastic behavior and thermal equilibrium. These features suggest that the MEs represent accumulations of early-formed mafic minerals, i.e., autoliths. Ferro-richterites from the Abu Kharif MEs are more magnesian than those in the host granite and together define coherent compositional trends – characterized by positive correlations of Al with Ca and Ti and negative correlations with Si and Na – indicating a progressive magma differentiation. These well-defined chemical linear trends observed in amphiboles further support a cogenetic origin of the host AKPG and its MEs within a shared magmatic evolution.