Titanite belongs to the common accessory minerals in Variscan (~ 360–350 Ma) metaluminous to slightly peraluminous tonalites to granodiorites of I-type affinity in the Tatric and Veporic Units, the Western Carpathians, Slovakia. It forms brown tabular prismatic-dipyramidal crystals (~ 0.5 to 10 mm in size) in association with quartz, plagioclase, and biotite. Titanite crystals commonly shows oscillatory, sector and convolute irregular zonal textures, reflecting mainly variations in Ca and Ti versus Al (1–2 wt. % Al₂O₃, 0.04–0.08 Al apfu), Fe (0.6–1.6 wt. % Fe₂O₃, 0.02–0.04 Fe apfu), REE (La to Lu + Y; ≤ 4.8 wt. % REE₂O₃, ≤  0.06 REE apfu), and Nb (up to 0.5 wt. % Nb₂O₅, ≤ 0.01 Nb apfu). Fluorine content is up to 0.5 wt. % (0.06 F apfu). The compositional variations indicate the following principal substitutions in titanite: REE³⁺ + Fe³⁺ = Ca²⁺ + Ti⁴⁺, 2REE³⁺ + Fe²⁺ = 2Ca²⁺ + Ti⁴⁺, and (Al, Fe)³⁺ + (OH, F)− = Ti⁴⁺ + O²⁻. The U–Pb SHRIMP dating of titanite reveal their Variscan ages in an interval of 351.0 ± 6.5 to 337.9 ± 6.1 Ma (Tournaisian to Visean); titanite U–Pb ages are thus ~ 5 to 19 Ma younger than the primary magmatic zircon of the host rocks. The Zr-in-titanite thermometry indicates a relatively high temperature range of titanite precipitation (~ 650–750 °C), calculated for assumed pressures of 0.2 to 0.4 GPa and a(TiO₂) = 0.6–1.0. Consequently, the textural, geochronological and compositional data indicate relatively high-temperature, most probably early post-magmatic (subsolidus) precipitation of titanite. Such titanite origin could be connected with a subsequent Variscan tectono-thermal event (~ 340 ± 10 Ma), probably related with younger small granite intrusions and/or increased fluid activity. Moreover, some titanite crystals show partial alteration and formation of secondary titanite (depleted in Fe and REE) + allanite-(Ce) veinlets (Sihla tonalite, Veporic Unit), which probably reflects younger Alpine (Cretaceous) tectono-thermal overprint of the Variscan basement of the Western Carpathians.